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中文核心期刊

窦部对称狭窄对颈动脉内流场影响的数值研究

Numerical study on the influence of a symmetrical stenosis at the carotid sinus on the flow in the carotid bifurcation

  • 摘要: 以颈动脉分岔血管为例,采用数值方法研究了窦部环缩狭窄之后的流场分布情况,并和正常血管情况下的流场分布进行了比较. 结果表明,采用环缩方式给颈动脉分岔血管施加对称的狭窄改变了颈动脉窦内流场,特别是壁面剪应力的分布规律. 低剪应力区出现在狭窄段之后的窦内,并且沿整个周向均匀分布. 根据低剪应力和动脉粥样硬化的关系,指出:若人为地给颈动脉窦内施加对称狭窄,则脂质沉积将在狭窄下游的窦内沿周向轴对称发展. 为了更真实地反映颈动脉窦内的狭窄,建议根据动脉血管中的实际狭窄情况,采用非对称的狭窄分布模式.

     

    Abstract: The operation of ring constraining, which produce a symmetricalstenosis to artery, was a usually used method to establish an animal modelor in vitro arterial atherosclerosis model because the straitness degree canbe controlled easily and quantitatively. However, it is unknown howthe flow field will be changed, and whether the flow field is similar tothat under physiological stenosis when a ring constraining employed tobifurcation or bended artery. To understand the flow in bifurcation arteryunder a ring constraining, carotid bifurcation with a symmetrical stenosisto the carotid sinus was instanced. The velocity profile, the secondary flowand the distribution of wall shear stress in the stenosed carotidbifurcation were numerically studied. The results were compared withthose inthe healthy carotid bifurcation. It was shown that the flow field in thecarotid sinus, especially, the distribution of wall shear stress, waschanged. Low wall shear stress was axis-symmetrically distributed on thewall of the backward site of stenosis. Based on the influence of low wallshear stress on atherosis, it was prompted that atherosis might take placeaxis-symmetrically in the backward site of stenosis. It is obviouslydifferent to the physiological process of atherosis. Therefore, it isindicated that the symmetrical stenosis is not suitable for simulating thecarotid sinus stenosis. To simulate the physiological stenosis in thecarotid sinus, an asymmetrical stenosis should be employed.

     

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